STOREDB:STUDY1015 GENRISK-T (FP6-36495) Iodine131-induced Thyroid Tumours in Mice [DOI:10.20348/STOREDB/1015]

Study meta-data


STUDYIDSTOREDB:STUDY1015
CREATEDON2015-12-10 16:26:47
MODIFIEDON2015-12-10 16:26:47
UPLOADERMichael Gruenberger
DOIDOI:10.20348/STOREDB/1015

Study details


STUDY NAME
GENRISK-T (FP6-36495) Iodine131-induced Thyroid Tumours in Mice
STUDY STATUS
Published: Open access to everyone
COUNTRY
Germany
PRINCIPAL INVESTIGATOR
Dr. Claudia Dalke
SPECIES
Mus musculus
BIOLOGICAL SAMPLE AVAILABLE
Yes
STUDY DESCRIPTION
To determine the extend to which individual genetic differences influence the risk of developing thyroid cancer after exposure to radiation.Genetic factors can modify susceptibility to the carcinogenic effect of ionising radiation. To establish if radioiodine-induced thyroid cancer is similarly genetically influenced, we studied F1 hybrid crosses between inbred mouse strains. Mice were perinatally exposed to iodine-131 and thyroid tissues examined after 18 months. Differences in the incidence and distribution of histological subtypes were quantified in relation to genetic background.
STOREV2_PROJECTID
http://131.111.32.76/store/project_details.php?projectid=19 (This project has originally been uploaded into the STORE v2 system and is still available here)

STOREDB:DATASET1029 Thyroid lesions in iodine-131 treated and unirradiated control mice. [DOI:10.20348/STOREDB/1015/1029]


Created on:2015-12-10 16:27:45 Modified On:2015-12-10 16:27:45
DATASET NAME
Thyroid lesions in iodine-131 treated and unirradiated control mice.
DOIDOI:10.20348/STOREDB/1015/1029
DATASET DESCRIPTION
Distribution of hyperplastic and neoplastic thyroid lesions in iodine-131 treated and unirradiated control mice.Different hybrid mice from F1 crosses of C3H C57BL/6 (C3B6F1), BALB/c C3H (CC3F1) and JF1 C3H (JFC3F1) were studied.
STOREV2_DATASETID
http://131.111.32.76/store/dataset_details.php?datasetid=21 (This dataset has originally been uploaded into the STORE v2 system and is still available here)