STOREDB:STUDY1066 Tumour and Life-time Study on Rats After Acute Neutron Exposure and/or Treatment with Para-dichlorobenzene and Tetrachlorobenzyltoluene [DOI:10.20348/STOREDB/1066]

Study meta-data


STUDYIDSTOREDB:STUDY1066
CREATEDON2017-01-30 12:31:52
MODIFIEDON2017-01-30 12:31:52
UPLOADERMichael Gruenberger
DOIDOI:10.20348/STOREDB/1066

Study details


STUDY NAME
Tumour and Life-time Study on Rats After Acute Neutron Exposure and/or Treatment with Para-dichlorobenzene and Tetrachlorobenzyltoluene
STUDY STATUS
Published: Open access to everyone
COUNTRY
France
PRINCIPAL INVESTIGATOR
Dr. Michele Morin
SPECIES
Rattus
BIOLOGICAL SAMPLE AVAILABLE
No
STUDY DESCRIPTION
Purpose: To assess the risks of neutrons in combination with a chemical carcinogen

Status: 1986 - 1990, data in ERAD

Treatment: Exposure to an about 100 msec flash of fission neutrons from the "SILENE" reactor (gamma/neutron ratio 1-40) and inhalation of para-dichlorobenzene (PCDB) or tetrachlorobenzyltoluene (TCBT); some groups received 6 injections of 25 mg/kg BNF at an interval of 15 days

Dosimetry: Double ionization chamber (Ar Te Gas) activation detectors (S, Ni, Mg, Cu, Au) passive semiconductor

Endpoints: Life-span study (spontaneous death) with macroscopic/microscopic pathology

Animal: Male and female Sprague-Dawley SPF rats aged 3 months

STOREDB:DATASET1106 Link to data and details in ERA [DOI:10.20348/STOREDB/1066/1106]


Created on:2017-01-30 12:32:22
Modified On:2017-01-30 12:32:22
DATASET NAME
Link to data and details in ERA
DOIDOI:10.20348/STOREDB/1066/1106
LINK TO FILE
https://era.bfs.de/studies_details.php?LabId=2&StudyId=13