STOREDB:STUDY1067 Tumours and Lifespan in Rats After Irradiation From Neutrons or Co-60 Gamma Rays and Treatment with Chemicals [DOI:10.20348/STOREDB/1067]

Study meta-data


STUDYIDSTOREDB:STUDY1067
CREATEDON2017-01-30 12:33:22
MODIFIEDON2017-01-30 12:33:22
UPLOADERMichael Gruenberger
DOIDOI:10.20348/STOREDB/1067

Study details


STUDY NAME
Tumours and Lifespan in Rats After Irradiation From Neutrons or Co-60 Gamma Rays and Treatment with Chemicals
STUDY STATUS
Published: Open access to everyone
COUNTRY
France
PRINCIPAL INVESTIGATOR
Dr. Michele Morin
SPECIES
Rattus
BIOLOGICAL SAMPLE AVAILABLE
No
STUDY DESCRIPTION
Purpose: To evaluate the influence of cofactors on the effects from Triton neutrons or gamma rays.

Status: 1982 - 1985, terminated; data in ERAD except for unavailable groups indicated in italics

Treatment: Exposure at the TRITON facility (fission neutrons 0.01-0.1 Gy/h) Silène reactor: see under 02.12 Co-60 source: (0.12 Gy/min)

Dosimetry: Neutrons: Carbon coated ionization chamber, Gamma source: Ionization chamber

Endpoints: Life-span study (spontaneous death) with macroscopic/microscopic pathology

Animal: Male Sprague-Dawley SPF rats at an age of 3 months, one experiment with Wistar rats ; for general controls see 02.01, for controls treated with BNF see 02.04, for controls with high dose neutron exposure only see 02.13.

Results: The only significant differences found in this study was an increase in lung cancers when BNF was used as cofactors

STOREDB:DATASET1107 Link to data and details in ERA [DOI:10.20348/STOREDB/1067/1107]


Created on:2017-01-30 12:36:45 Modified On:2017-01-30 12:36:45
DATASET NAME
Link to data and details in ERA
DOIDOI:10.20348/STOREDB/1067/1107
LINK TO FILE
https://era.bfs.de/studies_details.php?LabId=2&StudyId=14